Friday, 25 July 2014

Abstract on Artificial Vision

      ARTIFICIAL VISION
              Vision for Blind through Artificial Intelligence

ABSTRACT:       
            The five senses play a very vital role in the functioning of the human body. The loss of any of these senses is regarded as a major setback to many of the basic functions that were previously performed without any obstruction. Among the five, the loss of sight can turn out to be a major handicap to human beings. This can be understood perfectly by a simple experiment. If you try and walk through your own house blindfolded, you will realize a major difficulty just to cross from one end of the room to the other. Blindness turns many simple activities into impossible hurdles, which in turn makes one feel crippled in the world for the sighted. This is the kind of situation where science has the opportunity to help the human race to achieve normalcy in vision for all.
            There are a few medical procedures that involve replacing the defective eye with a normal one which is provided by a donor. Then are other procedures that involve the implant of chips into the eye, which simulate or mimic the process undergone by the eye during the generation of vision. This process definitely requires a rather large leap in the field of bio-electronics. In this paper we deal with the progress made in developing retinal implants that help regain lost vision in patients who suffer from retinitis pigmentosa and other related diseases. The basic idea behind this concept is to implant a silicon chip between the retinal layers and make the chip to perform its functions. Dr. William Dobelle, Dr. Dick Norman and Dr. Mark Humayan are the three scientists who gave headway in developing the artificial vision system.
Introduction:
            This paper deals with the diseases caused to the eye due to retinal damage or degeneration. Here we also discussed the scientific developments that have taken place during the course of time that will help in overcoming this problem.
Natural vision:
           A sketch of the anatomical components of the human eye is shown above figure. The main structures are the iris, lens, pupil, cornea, retina, vitreous humor, optic disk and optic nerve. .



                        We now know the basic function of the components of the human eye and how they participate in the vision process. Light that reflects off the objects around us is imaged onto the retina by the lens. The retina, consisting of three layers of neurons (photoreceptor, bipolar and ganglion), is responsible for detecting the light from these images and then causing impulses to be sent to the brain along the optic nerve. The brain decodes these images into information that we know as vision. There are a number of blinding disorders, which are primarily due to photoreceptor or outer retinal degeneration/destruction.       
                        Since the artificial eyes have not been developed, they must follow a specific guideline on how the device should be made and operated. One of the guidelines is the artificial eye must not affect the eyelids and muscles that surround the eye. It also has to be lightweight and must allow the eye to support the implant and lock it in place. The artificial eye must be able to manipulate the eye movements caused by the rectus muscles. The most important guideline to be followed is that it must be biocompatible, meaning it must be made up of materials that can be accepted by the surrounding tissues. This will prevent any infections, pseudo capsule formation and rejection of the implant.
Creating Artificial Vision:
                        The current path that scientists are taking to create artificial vision received a jolt in 1988, when Dr. Mark Humayun demonstrated that a blind person could be made to see light by stimulating the nerve ganglia behind the retina with an electrical current. This test proved that the nerves behind the retina still functioned even when the retina had degenerated. Based on this information, scientists set out to create a device that could translate images and electrical pulses that could restore vision.
                       Today, such a device is very close to becoming available to the millions of people who have lost their vision to retinal diseases. In fact, there are at least two silicon microchip devices that are being developed, and one has already been implanted in the eyes of three blind patients. The concept for both devices is similar, with each being:
·                 Small enough to be implanted in the      eye
·                 Supplied with a continuous source of power
·                 Biocompatible with the surrounding        eye tissue
                        Perhaps the more promising of these two silicon devices is the artificial silicon retina (ASR). The ASR is an extremely tiny device, smaller than the surface of a pencil eraser. It has a diameter of just 2 mm (.078 inch) and is thinner than a human hair. There is good reason for its microscopic size. In order for an artificial retina to work it has to be small enough so that doctors can transplant it in the eye without damaging the other structures within the eye

            On June 28 and 29, doctors at the University of Illinois at Chicago Medical Center and the Central DuPage Hospital, Winfield, Ill., implanted the first artificial retinas in the eyes of blind patients who had lost nearly all of their vision from retinitis pigmentosa.



Artificial Silicon Retina

            Preliminary tests from these FDA-approved surgeries have determined that the device has been biocompatible with each patient's eyes so far. It could be months before doctors know the results of these surgeries. They expect that the patients will be able to regain some vision that would allow them to see rough black and white images, but not with any detail or color

            The ASR contains about 3,500 microscopic solar cells that are able to convert light into electrical pulses, mimicking the function of cones and rods. To implant this device into the eye, surgeons make three tiny incisions no larger than the diameter of a needle in the white part of the eye. Through these incisions, the surgeons introduce a miniature cutting and vacuuming device that removes the gel in the middle of the eye and replaces it with saline.



Here you can see where the ASR is placed between the outer and inner retinal layers.

Next, a pinpoint opening is made in the retina through which they inject fluid to lift up a portion of the retina from the back of the eye, which creates a small pocket in the sub retinal space for the device to fit in. The retina is then resealed over the ASR.

                         For any microchip to work it needs power and the amazing thing about the ASR is that it receives all of its needed power from the light entering the eye. As you learned before, light that enters the eye is directed at the retina. This means that with the ASR implant in place behind the retina, it receives all of the light entering the eye. This solar energy eliminates the need for any wires, batteries or other secondary devices to supply power.

The Artificial Eye

            An "artificial eye" which would allow blind people to see is due to be implanted in a patient within the next few months. The device taps directly into the optic nerve and could restore some measure of sight to people whose retinas have been damaged or destroyed. Visual sensations, beamed from a video camera, are created in the brain by the artificial eye, directly stimulating different parts of the optic nerve.
            A video camera, positioned externally, transmits the visual sensations via a radio transmitter and microchip to an implant behind the ear. This is connected to the electrodes on the optic nerve. Different parts of the optic nerve are stimulated by altering the signals, similar to the way in which the electron guns in TVs are aimed at different parts of the screen. The electrode implanted, with wires leading out of the body to the signal processor, have been able to map camera pixels onto the corresponding parts of the visual field. This was possible because the subject was once sighted and knows what it means to "look at" something. The researchers hope the device will at least allow blind people to avoid obstacles, though more tests are necessary before the device is implanted. Most critical is the time it takes to realize they are approaching an object. If it takes 30 seconds to recognize an obstacle it will be of little use.


                                                        






 Natural Vs Artificial Vision:
            There are a number of blinding disorders which are caused primarily due to photoreceptor or outer retinal degeneration/destruction. These are not exclusive to diseases such as retinitis pigmentosa and age related macular degeneration. Tests have been made regarding the feasibility of developing a retinal implant/Chip, which could provide form vision to this subset of blind patients. This visual prosthesis would be situated in the eye cavity on the retinal surface. It would create the sensation of seeing light by electrical stimulation of the remaining retinal cells, which remain relatively intact despite severe photoreceptor loss. Moreover, by converting images into pixels and then electrically stimulating the retina by a pattern 3of electrodes, this device would recreate, at least, in part the visual information/scene.

Natural


          
                                                               Artificial


 In an otherwise totally blind eye, controlled electrical stimulation in patterns can produce vision compatible with limited mobility and can generate forms in the shape of large letters. The patients also often described seeing color and direction of movement. The details of these tests are provided in the following select references. However, as a word of caution, these results are from short-term tests. Evaluation is being done to check if these initial encouraging results uphold during more prolonged tests.



CONCLUSION
            Though there has been a major headway in the development of artificial vision. These conclusions are based only upon the initial tests performed in laboratories. What is required is sustained analysis and successful regeneration of vision which in turn will become the guiding light for many.
References:
1.     www.irit.fr
2.     www.acw.org
3.     www.wired.com
4.     www.brown.edu





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